Ever wondered “What is personalized lung poromechanical modeling and how can it improve the understanding and management of fibrotic interstitial lung diseases?” This is the question the Editor of Expert Review of Respiratory Medicine asked my colleague Dr. Pierre-Yves Brillet. And this is our best attempt at answering the question: [Brillet, Peyraut, Bernaudin, Fetita, Nunes & Genet, 2025, Expert Review of Respiratory Medicine].